Nitration of Tyrosyl Residues in κ- and αsl-Caseins
نویسندگان
چکیده
منابع مشابه
Transmembrane nitration of hydrophobic tyrosyl peptides. Localization, characterization, mechanism of nitration, and biological implications.
We have shown previously that peroxynitrite-induced nitration of a hydrophobic tyrosyl probe is greater than that of tyrosine in the aqueous phase (Zhang, H., Joseph, J., Feix, J., Hogg, N., and Kalyanaraman, B. (2001) Biochemistry 40, 7675-7686). In this study, we have tested the hypothesis that the extent of tyrosine nitration depends on the intramembrane location of tyrosyl probes and on the...
متن کاملPeroxynitrite inactivates tryptophan hydroxylase via sulfhydryl oxidation. Coincident nitration of enzyme tyrosyl residues has minimal impact on catalytic activity.
Tryptophan hydroxylase, the initial and rate-limiting enzyme in serotonin biosynthesis, is inactivated by peroxynitrite in a concentration-dependent manner. This effect is prevented by molecules that react directly with peroxynitrite such as dithiothreitol, cysteine, glutathione, methionine, tryptophan, and uric acid but not by scavengers of superoxide (superoxide dismutase), hydroxyl radical (...
متن کاملThe Reactivity of the Tyrosyl Residues of Cytochrome b,*
The reactivities of the tyrosyl residues of calf and rabbit cytochrome bs have been examined by acylation, iodination, and titration of the proteins. These experiments distinguish residues 6 and 7 as the most exposed and reactive residues, which ionize normally and can be acetylated or iodinated to form the monoiodo or diiodo derivatives. Tyrosine 30, which is common to both cytochrome preparat...
متن کاملThe reactivity of the tyrosyl residues of cytochrome b 5 .
The reactivities of the tyrosyl residues of calf and rabbit cytochrome bs have been examined by acylation, iodination, and titration of the proteins. These experiments distinguish residues 6 and 7 as the most exposed and reactive residues, which ionize normally and can be acetylated or iodinated to form the monoiodo or diiodo derivatives. Tyrosine 30, which is common to both cytochrome preparat...
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کاتالیست یک سنتز جدید برای تیواترها توصیف شده است. واکنش الکل ها با آریل، هتروآریل و آلکیل تیو ل ها درحضور 1،3،5- تری آزو- 2،4،6- تری فسفرین-2،2،4،4،6،6 هگزاکلراید ((tapc به عنوان یک کاتالیست موُثر، بازده های خوب تا عالی از تیواترها را حاصل می کند. علاوه براین، واکنش تحت شرایط بدون فلز و بدون حلال پیش می رود، بنابراین یک مکمل جالب برای روش های شناخته شده سنتز تیواترها ارائه می دهد. یک مکانیسم ا...
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ژورنال
عنوان ژورنال: Journal of Dairy Science
سال: 1969
ISSN: 0022-0302
DOI: 10.3168/jds.s0022-0302(69)86811-6